I voted "Yes" & have thrown away one guitar in my life: a Marlin Sidewinder (cheapo strat copy & my first 2nd electric guitar)
After a few years, it had become a total dog to play, I'd modded it heavily (including painting all sorts of cr@p on it with Airfix enamel paint), took it apart & couldn't be bothered to put it back together again. A music shop wouldn't have touched it & I'd have been lucky to even get £10 from a pawn shop, so I slung it in a cupboard & forgot about it. Several years later my mother contacted me (I'd long since left home, leaving the guitar in the cupboard) & asked if I still wanted it. I explained how useless it was to anyone so she binned it :)