Impedance ratios are FUN!
Ballpark figures, let's assume it's 5k ohms Ra-a with 4 output tubes to 4, 8, 16 ohms. Popping two tubes means you need to reflect 10k ohms to the primary because you've removed half the parallel resistance. That means your 4 ohm tap (5000 to 4 impedance ratio) with 8 ohms across if reflects 10k to the primary of the OT.
tl;dr - yes. Enjoy your Winged =C= growl.
EDIT: That's yes to half impedance by the way. Use the 4 ohm tap for an 8 ohm speaker.