had the aftermath installed in my les paul right after a cold sweat
main differences:
cold sweat: brighter top, crunchy but controlled mids, not much low mids, but bigger and punchier bass
aftermath: louder, middy as $%&# (mostly center mids), narrow low end, scratchy sensitive feel on picking and when moving your hands over strings
so I'd say the aftermath delivers a "djentier" metallic sound, but the the cold sweat felt punchier, despite of not having as much output and midrange aggression
like a less bassy, tighter and more organic miracle man
lead tone on the aftermath is thicker, but I like the cold sweats leads and harmonics better... they just sound more focused and organic.. sounds a lot like Ty Tabor (King's X) and Dimebag Darrell lead tones
you should reconsider the painkiller as well