I have a Les Paul with a Black Dog in the bridge, and a Mule bridge in the neck. I was looking for a neck pickup but someone was selling the mule bridge locally so I figured I'd save a few bucks and try it.
It sounds fine to me but I'm not a huge neck player. It pairs well with the Black Dog in terms of output, and has a great woody tone with maybe a bit more power and bite than your typical neck.
I don't think the mule bridge and neck are that far apart in output anyway.