I think the MQ would be hot enough to work with the Mule or SM, but I don't know what sort of tone you'd get combining them. Is the guitar wired so you get middle+bridge in the middle switch position? You'd never get the MQ on its own.
I think it would be cool to have MQs in middle and neck positions, with a humbucker in the bridge. You could rewire the switch to give you neck, neck+middle, bridge.