I had a tele with a Yardbird set and a 4 way switch. It definitely 'works', but personally I found that the Yardbird bridge didn't have enough balls for what I wanted (I guess the YB bridge was slightly too traditional for me). So, I paired the quite frankly exquisite Yardbird neck pickup (the best tele neck pup i have EVER used) with a Piledriver bridge instead. IMO, this combination is bloody amazing and the in-between (both in parallel) is just excellent. The series position of these two is a monster.
However, I should say that the name of Piledriver could lead people to believe that it is inarticulate and OTT. Not at all. It is a hot bridge, yes, but still very expressive in my view (particularly if the height is not set excessively high, which is sometimes a temptation with less hot bridges). Roll back the volume and all the traditional twang is still there.
I have to confess that in everyday use I don't use the series position often, buts its nice to have and does get used now and then. This position was probably more useful with both Yardbird pickups rather than YB neck and PD bridge - the series setting in my current setup is like a sledgehammer because of the power of the PD - the parallel setting is more useful.