I think basswood guitars work best with higher output pickups. Since the natural tone of basswood is quite "lightweight" and neutral it can handle a pickup with lots of power, bass and mids. For example - without getting into a DiMarzio slanging match - lots of people use Tone Zones in Ibanez RGs with (apparently) good results, but I put one in my SG and it seemed to accentuate the guitar's natural middy tone into a huge, horrible boomy mush.
I'm now thinking of putting a Warpig in my SG. I'm a bit worried about the high output, but I guess it should work, since we all know what kind of guitar Tony Iommi plays!