It's funny you ask that as I was just playing through my Quickrod
Long story short, through an effects chain (in front of the amp) its not much of a difference, but put it through a an effects loop and you can't help but grin. I have been feeling down on my tone lately, and while it's not quite where I want it yet, this pedal makes me want to play more and more. The difference is quite literally night and day.