I have custom-wound pickups similar to MM in one of my Strats. Those pickups are bright, in a vintage way. If you like that sound, you'll like those pickups. If you are after a more modern tone, go with something like Irish Tours. Compared with the CS '69 pickups, my pickups are more midrangey than bright.
If you like that "hollow" midrange Strat sound, you'll prefer the CS '69. If you are like me and cannot stand it, get the MM.
Like many actual vintage Fender pickups, my pickups handle overdrive, but to a point. I would say that they handle 'drive better than the CS '69, but YMMV.
I also have a trashed CS '69 that was re-wound by Tim for the middle position of one of my other Strats. Now that is a bomb-ass pickup. Very lively and bright but with no ice-pick in the ear. I don't know how Tim and his Merry Men did it, but I like it.