If you're sure it's not the valves, check the effects loop solder job. I had one buddy who brought me his with a considerable volume drop and I found the effects loop soldering to be sub-par. Cold, dull, gray and cracking solder. Redid the joints and it was right as rain.
Anytime I have an amp problem I do a few things first before opening it up:
1. Try different leads, guitars
2. Make sure all settings are correct, front and back
3. Check pots for scratchiness or odd feeling, check jacks for loose feeling, dead battery for active pups etc
4. Plug straight into the effects loop's return, if it has one(see which half of the amp is the problem, preamp or power section)
5. Leave it alone for a bit as I'm too pissed by then to really be thinking about things
6. Find a schematic
Let us know what you find out. I'm OK at trouble shooting, but there's guys on here with TONS of knowledge. I'm sure it can be sorted out. :D