I put 4 Classic Leads into a Marshall 4x12 cabinet.
The Classic Leads are very good speakers with a massive amount of mids, and a tone much smoother than any other speakers I've used. A few things worth noting is you won't get classic tones out of them where you will out of V30s as they're more modernly voiced. They also have less presence than other speakers, so you will want to turn your presence up a little higher than normal.
I would say the V30s are the best do-everything speakers I am familiar with but the Classic Leads are my favorite.
I would probably put the classic leads on the bottom because they have a lot better low end than V30s but only if you're playing a large room. In smaller rooms, an X shape might be the way to go.
For what it's worth, I absolutely hate T75s with their scooped mids and fizzy highs and lows that sounds someone has bad gas (the best I can describe it). If you think V30s are fizzy, the best advice I can give is to skip right over them. Personally there was not one tone I'd ever want that they did remotely decently, and that's not something I say lightly -- they're just that bad. And for what it's worth, most of my guitars and amps are very middy, I'd time the mids and it would still sound rather scooped. The highs are fizzy, but weren't extremely overkill either, just fizzy.
I'm not too familiar with Eminence speakers so I can't get a good cross reference.