So before I get too far into this, my favorite guitar is an ugly parts-caster. I acknowledge it's lack of beauty, but I love the thing and I just might weep if it was destroyed/lost. That being established, it's been through a number of changes since I first slapped it together: different paint jobs, pickups, tuners, a neck swap or three and three different wraparound bridges.
I started with a Hipshot baby grand (aluminum body, steel saddles and studs and brass body inserts). Too bright overall and the high e and b strings came in contact with the aluminum body where they weren't supposed to causing the paint to wear away and a groove to start forming behind the saddle. Fine sustain, quality build, just not working for me.
The next bridge I tried out was a Gotoh 510ub (all zinc with hardened saddles). Very dark, lacking sustain compared to the Hipshot. I bought some titanium saddles from FU-Tone and the sustain and top end came back in spades (although the low end was always a bit tubby) but I hate the way strings are loaded into it (it's very easy to have strings run across the guitars finish, I had to be super careful when re-stringing).
Now I've recently installed a Graphtech Resomax Sonic 1 (completely made of their proprietary alloy). I had to drill out the body holes a bit to accommodate the inserts, but I'm rather glad I did! More sustain by far than either incarnation of the other two, no flabby low end, harmonics of all sorts abound, squeals are near effortless, it's stupid light and I never knew I could have this much note definition without harsh high end! That being said, it does not have adjustable saddles (which I was hesitant about). But so far I've just intonated the low and high e's and nothing has sounded funky. I emailed Graphtech and they said the bridge was designed around a 'standard' set of 10's. I use Roto' RH9's and, like I said, the intonation sounds great to me (you're mileage may vary).
For reference, my guitar has a 25.5" scale length if any of you were curious. I also acknowledge that no piece of gear is perfect. I hope the day finds you all well.
