I do not know how the whole ohm thing works on a guitar head to the speaker cab. I would love to know, but I do know a lot about car audio and can tell you what I know from that. The amp in a car has no ohm setting. The ohms are determined by how u wire the speakers "Parallel or Series".
The lower the ohm load the more volume you will get with less clarity. The amp will heat up a lot fast in a low ohm setting. Low ohms are used in car audio for bass, since bass really does not have to be crystal clear, just loud.
The higher you go in ohms the less output you will get but with better clarity. Your amp will not get over heated.
Other considerations are the rms wattage per speaker you have and rms wattage your amp can supply. thanks chris