If you go into the tunnel from the west side (11th ave), it is usually the fastest. An alternative is the GWB and then the Turnpike to the Lincoln Tunnel exit, Hoboken is the last exit off 495.
I did the beer run last night and bought all the Dirty Dicks that they had (15 pints!). I also got some more Sam Smiths (Imperial, Oatmeal and Old Brewery Brown), Boddingtons, Murphys, Wytchwood Hobgoblin and Fiddlers Elbow, Black Sheep (Ale, Riggwelter and Holy Grail) and Fullers (London Pride and ESB). I think we should be OK for beer!