Try it with whichever guitar your Mule is in :P
As for speakers, I guess V30s would get me closer to the tone I want, but I thought they were more suited to metal, whereas I play classic rock, hard rock and cheesy 80s stuff :)
How about a V30 in the bottom of my cab (heard its quite bassy so would be good for the bottom) then a more rounded top speaker?
I heard fps_deans clips and his Classic Lead cab sounds perfect although I dont know the voicing of those speakers..