I know that John McLaughlin was a big Axon user, mostly with his Wechter nylon string with built in midi. I think he said in the advertising that it's the only system that could track as fast as he can play.
Now with his Godin and Mike Sabre guitars he uses a Roland GI-20. It's only an interface, no internal sounds so you still need a synth module or maybe you can use Cubase plug-ins on your computer, John uses the sounds in Apple's Logic Pro.