if you put a quad of KT88s or 6550s in an EL34 amp you'll not really get any more output. EL34s have a maximum dissipation 25w a piece whereas 6550s and KT88s (depending on what you get) are 42w each. to get the full rated power, you need an output transformer that will handle that wattage.
what you WILL get though is a tonal change - 6550s and KT88s will just give you a much lower and tighter bass with lots of punch and headroom. this sounds great if you run any kind of gain with an aggressive style. downtuners will love this too.
Newer EL34 amps will have a fairly reasonable plate voltage (450v'ish) so you're fine for running 6550s and KT88s without any modifications. 6L6 amps otoh will often have the bases wired slightly different (pin 1 used as a tie point for the bias snubber resistors) so don't plug other valves in without checking this out first.
:twisted: