Depends what strings are currently on there already.
You can calculate the string tension for each string, add them up for both sets and see how close you'll be. It might take another spring or two in the floyd, assuming the neck has enough strength to cope with the extra tension... they're not that heavy strings, I set my backup RG up with 13-60s in drop A (from 10s or 11s in standard tuning, I forget now it's a while ago).