It seems to me that most of the calibrated sets are quite "gently" calibrated, i.e. the variation in tones between neck and bridge is subtle, not a really dramatic contrast. Which is, really, how they should be.
I'm more of an unsophisticated oaf and I like the neck and bridge pickups to sound very different - fat and warm neck, bright and crunchy bridge (usually). So for me, mix & match can work really well (if I manage to choose a good combination).
The most important thing to remember is that each calibrated set is made up of two different pickups, one designed for the bridge position and one for the neck. The Cold Sweat neck, for example, is NOT the same pickup as the Cold Sweat bridge. So whatever models you choose, just make sure you pick a neck pickup for the neck position and a bridge pickup for the bridge. Unless you deliberately want to do something different.
If in doubt, you can always check with Tim before ordering.