The Crawler/Mothers Milk is a great set up, though I've been thinking about the Black Dog with 2 Slowhands for a rock guitar, but this might be more of a classic rock set up.
I have the Crawler with 2 Alnico IV P-90's and this is an awesome combination. The P-90 has a bit more drive than a Strat pickup, but still gives you that single coil sound. If you are having a guitar made, you could go with this.
Last but not least, for a lot of power with classic tones, I have a Nailbomb with 2 Trilogies. This gives you a lot of drive to the amp.