Hello ( and welcome ). :)
I have no direct experience of the 'Sinner' bridge pickup - only the Mississippi Queen. I am thinking that if it was me, I would go with the'Sinner' - as the M.Q. is very nice, but not really ultra 'hot' in the context of the sort of playing I think you may be describing.
The conventional wisdom ( on the Strat with low to average output ) seems to be one Stormy Monday Humbucker in the bridge, or a VHII to match already hotter mid and neck pickups for those E.V.H. 'Frankenstrat' moments.
I would therefore save the extra work in routing out the guitar body ( or if already routed, buying and re-wiring another scratchplate ) - and just get the very potent Sinner to sit like a wolf in lamb's clothing, there in the existing bridge slot.
I hope some of the forumites with more specific Rock playing experience chime in though . :)
Of course there are a whole range of medium hot / fatter Strat pickups - like Mother's Milks e.t.c. - but again, I have never owned a B.K.P. Strat pickup.