I've had an E610
Savage 120 head since
2007 & I love it, even more so since I
got my 4x12 cab last year.
It has every sound I really need, is capable of immense volume yet still sounds great at low levels - the 6550 power section is so clean & can reproduce great tones right down to almost conversational volume. The more I play with this rig, the
happier I get:

Before that I had a Mesa Single Recto. It was a nice amp with a warm lush clean channel & thick sludgy metal gain, but as my playing evolved I started to need an "in between" third channel - something just breaking up into light drive. So I started to look at 3+ channel amps.
If money was no object, I'd have bought a
VHT Ultralead (I still cling to the belief that one day I'll own one of these...) & for a very long time the
Hughes & Kettner Triamp MKII made my credit card very itchy (how could I
not want to own the amp of my hero, Alex Lifeson?). I had also tried an Engl Powerball & liked it a lot.
Then with the Exchange rate, getting an Engl from Thomann started to seem like a good bet. I couldn't find anywhere to try out all the models so I was wavering on whether to just buy something I knew or take chance on something I didn't. Then a work colleague from Munich (who owns or has owned just about everything ever made by Engl, H&K, Diezel etc) convinced me that if I liked the Powerball, I'd love the Savage (the two FX loops really appealled to me) & he was dead right.
I'd be lying if I said I don't ever look at other amps - I'd still like an Ultralead, a Triamp, perhaps a rack with an Egnater or an Engl SE preamp. But they would only be for variety - the Savage would remain firmly my #1 rig :)