As far as the Amp goes, It's not got ridiculous amounts of gain, the 6L6's give it a good crunch and seem quite smooth to me - gain levels approach Iron Maiden levels, so i was thinking MM to give it a push and to stay smooth.
apologies for the essay, just making sure i don't leave anything out.
My main priority is a tight, thick rhythm sound which emphasizes pinch harmonics really well. I only have experience of the MM, NB and Crawler and want to move away from the NB as i have them in two guitars already.
Mids aren't a problem for me, i tend not to scoop them on the amp, which is why i probably like the MM, it seemed to have the right amount of scoop in my les paul.