I think you might be overthinking things a tad. everyone on this forum "mismatches" pickups. just because there's such a thing as an aftermath calibrated set, it doesn't mean that the aftermath neck and bridge are better than a painkiller neck and aftermath bridge for YOUR tastes.
unless you chill in the middle position a lot, you're probably someone that uses his bridge pickup for certain things and the neck pickup for certain things. if you dont like the bridge, but you like the neck, just switch the bridge.
fyi, a popular combo is painkiller neck and cold sweat bridge, and another popular combo is cold sweat neck and painkiller bridge (pretty lol imo). Tim just names the pickups as he sees them fitting together, but if YOU found something you like in the neck but not the bridge, just switch the bridge.
EDIT: forgot to mention to just switch the bridge pickup ;)