I have two Duncan single coils and a BK Crawler. In fact this was one of the first things I tried... I tried to cancel out every factor I could (nut, frets are in good shape, with relief or flat neck, pickups at normal height or all the way down).
In fact this was part of the reason why I wanted to lower the string height; at 5mm off the fretboard, I need the pickups higher than normal. But when I fret notes, they get very close to the polepieces (too close). It also makes it even harder to balance out the single coils and the humbucker. With the strings at a more normal height this issue would have been solved.
Thanks guys... I know I did something weird somewhere down the line. I've reset the neck straight as can be and I'll re-work the setup from scratch. Strings are new.
I think mostly I'm disappointed that this happened. This guitar is my baby and I'd never had any buzz whatsoever before, I knew her setup by heart and her and I had a healthy relationship... ;) Whatever's left of my pride is a wee bit hurt!
Another factor is that the appartment is very warm due to it being cold outside. Warm and dry though. That's why I had to adjust the neck in the first place.