Bear in mind that with regard to the output, its going into a DI and ampsim. The benefit you get from hitting a preamp harder is nullified by
A: lack of actual preamp clipping. No valves to hit harder, emulation only.
B: gainstaging - input, if the OP knows what hes doing (I'll give him the benefit of the doubt) is going to be to a mic pre with the gain set such that the DAW will show -18dbfs regardless (0VU, +4db, 1.24V, nomnial optimal level for all audio gear, including the mic pre). Less that that and your SNR is less than optimal, more than that and youre just getting distortion from the mic pre.
Unless hes using US hardware in which case its -12dbfs. The voicing of the pickup is all that matters, not its output. It would be better to have a lower output pickup with a clear character, lots of mids and top end, than a hot and heavy pickup that would hit a guitar amp pre harder.