Depends on what tone you're going for. Many players don't seem to hear the differences between treble and presence.
If you keep the presence down low, you don't get that aggressive grind from the amp. I use the treble to control the amount of 'cut' I want, then dial in the presence afterwards.
My EQ on a 2203-based circuit is:
Gain: 7/8
Bass: 6/7
Middle: 9/10
Treble: 5/6
Master: 2-6
Resonance: 3/4