I've played a jet city 50W extensively in a local place and it shares a lot in common with its big brother, the Soldano HR 50+ which i'm lucky enough to own because i found one at a very low price a few years back when the economy was shite and every one was doing fire sales.
In short these amps love pedals but you don't need for most things excluding extreme preamp distortion styles. I wouldn't use a screamer because they're an extremely mid rangey amp to start with. everyone does the clapton, knopfler, moore assosciation, but i think you've got way more in common there with cantrell, slash etc. you can back off the mids for a scooped tone, but these amps are built to cut thru a mix live. Steve via used to use the SLO100 in his live rig so you got virtuoso stuff covered. the first channel is actually pretty clean if you want it to be, but i use it for 70's rock, with a good boost it nails things like skynards solo tones. otherwise i know jazz players use SLO's and HR50's for the clean channels, blues guys like the dirt in the first channel when the gain is up, and everyone from hard rock to heavy metal go for the lead channel. Basically this amp plus a few choice OD's, boosts and fuzzes and some careful eq'ing and careful guitar tone and volume controls can do most anything.
the Jet city 50Watter is 85% of the way to a full fat soldano for a 5th of the price
