I have 4 Strats with humbuckers in the bridge:
Crawler/IT/IT - Alder Body, Rosewood fretboard
VHII/VHII - Alder or Basswood (not sure, its an 84 Jap Strat), Maple Fretboard
Cold Sweat - Ash Body, Rosewood Fretboard
Non BKP (PM if you want more info) - Agathis body, Maple Fretboard with Kahler Trem
In my opinion, any of these combinations would get you to where you want to be tonally as I play similar stuff to you myself so can speak from experience.
The Crawler is essentially a PAF on steroids so is very versatile and can cover a lot of ground and isn't too in your face. The VHIIs sound alot more open than the others, still very versatile and I find running them in Parallel also gives good single coil-ish sounds. The Cold Sweat isn't that great on cleans, not sure if that matters, but really excels with gain. Quite an aggressive sound, but not too much so that it pulverises everything else but it's also nice and full.