I always really liked the 'S' series. Lovely guitars without being as overtly 'Metal' as some Ibanez products.
Back to pickups :D
For Metal, the Holydiver is my favourite bridge pickup and will certainly work beautifully with a Cold Sweat in the neck, though I prefer it with the Emerald in the neck. The extra thickness you get in the Holydiver compared to many 'Metal' pickups helps to give the tone real body, which will help with your guitar as it's so thin the mahogany will be having little effect. I also tend to like things smooth and fluid with a bit of aggression, which is exactly what the Holydiver gives you. The focus on mids also means it cuts through really well. If you think of Doug Aldrich and Jake E Lee era Ozzy, you'll be in the right ballpark. Leads are fantastic and really sweet with plenty versatility thanks to the alnico V magnet. For a 'Metal' pickup, it has surprisingly good cleans. I see you've already had a Miracle Man, which is another of my favourite pickups and has a number of things in common with the Holydiver. Both are thick, smooth and fluid, it's just that while the Holydiver is all mids, the Miracle Man sounds a bit more scooped as the mids are more low mids than anything else though they're nothing like as far apart as the EQ on the website would suggest. Think of the Miracle Man as a Holydiver with more botom end, more screaming highs, tighter and with worse cleans. The Holydiver is certainly more versatile and with the help of an overdrive pedal, will get you into very similar territory to the Miracle Man.
The Cold Sweat is a different beast entirely. Being ceramic, it's a much tighter pickup and given its Metal application, I always found it surprisingly open. It's a lot brighter than the Holydiver and that would be my concern in relation to your guitar. If you like things brighter anyway, it will be fine. I had mine in an RGT42 but in those days I liked things brighter and tighter than I do now. The cleans are remarkably good for a ceramic pickup but not in the same league as the Holydiver.
The A-Bomb tends to split opinion a bit. I sent mine back because it didn't suit the guitar I was using it in (Jackson Soloist) yet I still find I think about it as an option for future projects. It's a really hot pickup yet somehow retains an element of PAF openness. I have no idea how they achieve that because it does sound very modern in style. It's a big tone but bear in mind the upper mids are very aggressive sounding. It's a really hairy sounding pickup with a distinct edginess to its tone and not only is it the tightest alnico pickup I've tried by some margin; it's also pretty much the tightest pickup of any kind I've ever tried. If you like things to sound very tight and aggressive, this could well be for you.
