I prefer Gotohs, and they do make a tuner which will directly replace Grovers (without having to drill new screw holes). Quite hard to get hold of the right ones though, especially in gold.
To fit Planet Waves or Sperzels you'd have to enlarge the holes for the tuners to 10mm (or 25/64" or whatever it is), all the way through the headstock. I wouldn't do it!
The locking Grovers are OK though, and not much heavier than the non-locking ones.