well, yeah, the vox is vintage sounding. My savage se actually sounds a little like a vox on the crunch 1 channel, in triode mode, because triode mode has more natural compression etc., like a vox- but that's the only engl that really sounds like that.
the vox will be no-where near as versatile as the engl. At low volumes, you're struggling to get it much heavier than classic rock (haven't tried it with an OD though). It'll be better at the vox tone, but the engl will be better at everything else.
EDIT: the engl's distortion, assuming you like its voicing, will sound better than the Vox + OD pedal.
The engl's range of tones is amazing, quite frankly. By just switching my footswitch, i can go from a fendery bluesy yet jazzy, warm clean, to a vox-y/fendery/marshally (mixture, lol) kind of classic rock crunch, that sounds bluesy with single coils, to classic metal (maiden) and 80's hard rock and hair metal, to sweet, smooth shred solos in smooth mode, to brutal modern metalcore (think killswitch engage) in rough mode. EDIT: did you check out my dmusic site? I posted it in that other engl thread.
And the SE is just heaven. Every friggin tone under the sun is in there. Seriously. And they're all amazing.
Now, the screamer doesn't have just this range (doesn't really have the smooth shred tones- now you could probably dial this in, but you'd lose the killswitch engage tone, since you'd have to dial in a less trebly heavy lead channel), but it has fendery cleans (with added sparkle), marshall but brighter crunch, hard rock soft lead channel, and modern metal heavy lead channel.
I haven't tried an amp with a wider range of tones than an engl, and I've tried virtually every amp it has been possible for me to try.