I've never played D-standard before, but have Eb - loose, but a good loose. However, I just got with a power metal/prog band whose singer needs us to drop down to D to optimize his vocal range. I just strung up my 25.5" Ibanez with .10s, and reset the action. The playability is super - low action, no buzz, etc, but unlike Eb, I don't find this a "good loose". It seems almost on the verge of flubby. It doesn't seem to have the punch in rhythm playing as tuned to Eb, and certainly not E-standard.
I'm playing with a Holydiver bridge and Emerald neck through a mesa MkV. Usually love it. Not sure I want to go to .11s, but maybe I'll have to. Could it be pickups? Do others play .10s in D-standard on a 25.5 scale and like it? I usually play .9s in Eb, so thought .10s in D would have sufficed. Anyone?