Yes it will work. The higher the volume pot value, the brighter the tone. Since it is a very hot pickup in the neck, it should sound fine. If it is too bright for your taste, you can run a resistor in parallel to have 250kfor the Cobra. When I wired up a Super Strat with a Holy Diver in the bridge and an Irish Tour in the neck, I just used a 500k pot for both, and the Irish Tour sounds good with the 500k volume pot.