Brian May is 1 of my favourite guitarists if I'm totally honest!
He just seems to have a great sense of Harmony and Melody that I don't hear in alot of other guitarists.
I'll also agree that he has a very 'individual' guitar tone. You can usually tell straight away that it's him playing something just by his tone.
And for the record, the studio version of 'Crazy Little Thing Called Love' was played on a Telecaster and a MESA Boogie combo. Brian told the producer that he could approximate a Tele sound with his RS, but he was told 'if you want to get a sound like a Telecaster, use a Telecaster!' so it seems that he was pressured into it! :lol: