Ok here's a small clip of my Mule, quick and dirty.
Guitar is custom made solid body cedar/maple top HSH, comping is made on the neck/middle (SD Jazz/Heaussel blues), solo is on the Mule.
Played on a Mesa nomad with an HK Red Box after the preamp (it's 22:30!)
I added speaker simulation in Cubase on the lead to smoothen it a bit. I might try to do a better job saturday when I can use speaker and mic, and more tone variations.
But this should give you an idea of what a Mule can do with gain.