Minimanlism is the Key. I like one basic good sound, none of this intergrated effects gubbins! An amp is just an amp, and I like to keep things basic and use stomp boxes to change the sound the old school way. I am currently using the Vox VR30 amp, which I bought for its amazing tone, it has 2 channels, but they both sound great. So I have 2 channels to work from, I tend to use the treble booster a lot with the dirty channel for soloing, and sometimes with the wha added, it sounds great, everytime. Especially with the Mule humbucker its a fat sound.
regards,
Ben.