To me, one of the great all-time killer 335 tones is courtesy of Alex Lifeson. And his wasn't your creamy, vintage, grandfather's 335 tone. It snarled, it bit, and and it would sustain like a mofo.
Listen to Moving Pictures. Through a Marshall or Marshall-esque amp (like a Roccaforte or Splawn) you can get that tone, possibly with either the SMs or the VHIIs, but the VHIIs would get it quicker, easier, and without having to reinvent the wheel. ;)