The other guitarist in my band has 2 MQs in his 335 copy and it sounds excellent! From melt-in-your-ears plummy (tone backed off a tad, lovely for jazz tones) to growly, from crunchy to wailing and it takes gain exceptionally well, biting but not in the least ice picky and sweet in all registers - just the opposite of the humbuckers that were in there before. It also doesn't suffer from excessive hum unless you are really near the amp under high gain (He uses a Fender supersonic and a Rivera).
I don't think you can do any better than MQueens, but, as always, Tim is the final court of appeal.