I wouldnt go for a painkiller for that.
Its too middy and too crunchy. Thats a smoother, treblier tone.
From the clips and descriptions I've heard, the HD would get you there.
From what I've played, thats a miracle man with the treble rolled back a bit more than normal, or a warpig with the gain a bit lower than hes probably playing it with.
For the record, the Painkiller sounds very different than the 500T. Similar DC and magnet, but theres way more to it than that ;)
Edit: I played an Uber with a C-Pig. I didnt dial that exact tone in, but in my twiddlings of tone that was definately in there, so thats an option too.