I think if you're the kind of person to be anal about such things then it makes a difference. I dont think THAT many do use ribbon wire.
If you get overly paranoid about things breakin

g, then you might want to look for something put together in a particular way that suits you. Thats how I felt when I was buying an amp a few years back. I'd also wager most amps don't see the harshest conditions they could see. (getting liquids thrown over them, getting dropped out of vans, getting pulled out in minus 42 degrees so the condensation in them freezes).
I think most damage like you say, if any, is repairable. But for me it came down to how much it costs to get those things repaired. I've had people refuse to even look at my amp based on it being high gain. I've had people want me to pay them just for giving me a quote on fixing an amp. I still got a PCB amp though... haha. Just one that I thought would be reliable... much like the Invader i guess, but I don't like the ENGL sound. I also don't trust Marshall build quality.
I don't have a problem with mass production or keeping costs down. again, as long as its not done to level that impacts safety or whatever.
I mentioned the Herbert because I don't think the ribbon wire carries a large voltage but rather FX Loop signal.
Another cool design... the Peavey Classis 30 PCB... simply unfold to fix! by the way, the metal jumpers across the gaps that you bend when opening that are actually in circuit. It's things like this that lead to materials and methods getting a bad rep.
