Yeah man, I used to whack everything up to max when I was 15 / 16, but obviously that's because I thought "that's what you do to play TEH BR00TULZZZ!!!
Ever since I really got a taste for really exploring sound and broadening my horizons, from the age of 17 onwards I used to experiment with halving my gain and, if recording, layering two or three guitar tracks. You get a really nice, defined sound, but with all the distortion you need!
Unfortunately I've had to scale my rig down over the years to accommodate my living situation, so I only really use a Pod now, but now that attenuators have become more stable, reliable and commonplace, I am saving for a full all-tube rig again. There's nothing that beats a really cranked tube amp at about half gain on the crunch channel and a TS / Bad Monkey (or any comparative pedal) to colour it and give it that little bit of pedal-powered bite. :D
So less definitely is more!